March 2015
IN THIS ISSUE
 
Winter Seminars 2015
 
Summer Course on Mood, Aggression & Attraction
 
Special Lectures 15
 
Tuition fees/Grants 15

 

 
 
 
 
This is the newsletter of the International Master of Affective Neuroscience and the Summer School on Anxiety and Depression.
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Impression Winter Seminars 2015
winter seminars 2015
Our winter seminars were held the last week of February. Below an impression by one of our students: Bjorn Cartlegde (on the photo first person on the right side standing against the wall).
 
Winter School 2015
 
This years winter school was held over five days in Maastricht and covered the neuroanatomy of depression, hierarchical defence systems, gene by environment techniques in research and two days on social cognition, anxiety and emotional memory.
 
The days were busy, but stimulating, with excellent presentations from each student on the reading materials and fascinating discussions within the small group. Having a broad range of experiences and backgrounds, as well as a faculty member to guide discussions made for a productive approach to each problem. The high workload of reading and preparation paid off in the insight gained into the topics mentioned above - all at the cutting edge of research in our field. 
 
Maastricht itself was a great place to spend a busy week, and transport and accommodation was easy to organise (with some recommendations from Wendy)!
 
Overall, the Winter School was busier than the Summer Courses but with a much smaller group it managed to be very enjoyable as well as productive!
 
Summer Course on Mood, Aggression & Attraction 2015: Register now
From 28 June - 3 July 2015 the International Master in Affective Neuroscience organises the
Summer Course on Mood, Aggression and Attraction in Florence, Italy. 
 
Please click here for the programme

The Summer Course on Mood aims at an in-depth analysis of the latest developments in the field of depressive and bipolar pathology, including phenomena that are related to Mood such as aggression and addictions.
It is aimed at young scientists and clinicians with a background in psychology, medicine, neuroscience, behavioural sciences, or a related discipline, who want to enhance their expertise in affective disorders.
 
Early applications: 15 April 2015
Final applications deadline: 15 May 2015
 
Special lectures during the Summer Course on Mood, Agression & Attraction 28 June - 3 July 2015
Each Summer Course, we present lectures and workshops by our own faculty but also a series of guest lectures by esteemed scientists from all over the world. The following special lectures will be presented this year.
 
The Servier Lecture will be held by Prof David Kupfer (Pittsburgh) and Prof Jim van Os (Maastricht). For the ECNP Lecture, we welcome Prof Gitte Moos Knudsen (Copenhagen).
Prof Joseph Zohar (Tel Aviv) will give the AFN Board lecture.
 
 
Prof David Kupfer (Pittsburgh):
Pros and Cons of DSM-5:  the Case of Prodromal Syndromes
 
For the purpose of diagnosis, psychopathology can be assessed at different levels of temporal resolution. Thus, episodes of illness can vary over a period of months, for example an episode of anxiety being followed by an episode of psychosis. However, psychopathology can also be assessed at the level of fluctuating symptoms, varying from day to day. Finally, psychopathology can be assessed at the level of fluctuating mental states that vary from moment to moment in the flow of daily life.
 
The development of the DSM-5 represented an open series of debates concerning numerous changes proposed for the revision, some of which were eventually adopted. Among the major changes proposed, a most interesting one was Attenuated Psychosis Syndrome (APS). APS contained all the ingredients for good debate, since it involved clarification of terms, issues of development, early intervention, stigma, and potential overuse of medications. While the DSM, itself, is not a set of treatment guidelines, the diagnostic criteria can clearly play a role in terms of providing the impetus for treatment recommendations. Differing views throughout the world on the nature of “at risk” populations, the differentiation of psychotic behavior into better-defined syndromes, public debate on the potential risks associated with adopting this diagnosis into the main section of the DSM, and the data on conversion to psychotic and non-psychotic syndromes all focused attention on this syndrome throughout the seven year period of work on the DSM-5.
 
Our discussion will provide a revisit to the process that led to the placement of APS among conditions for further study, the pros and cons of that decision and its implications.
 
 
Prof Gitte Moos Knudsen (Copenhagen):
Neuroimaging of Affection and Aggression
 
Understanding what predisposes individuals to affective disorders or impulsive-aggressive behaviour is critical to take preventive measures that aim to avoid development of full-blown depression or to violent acts. The interpretation of observed brain imaging outcomes in patient groups may be hampered by concomitant or preceding medication, or perhaps some of the observed differences are effectively trait and not state markers of disease. There are different ways to investigate mentally healthy individuals that are vulnerable and carry an increased risk for affective or aggressive disorders.
The neurotransmitter serotonin is considered to play a main role in both conditions and consequently, imaging of the brain serotonin system could provide important information as a biomarker for vulnerability to diseases. Magnetic resonance imaging (MRI) and positron emission tomography (PET) offer two complementary techniques for in vivo investigation of the brain. Imaging aspects of different approaches (at risk populations, personality traits, interventions, ...) will be covered at the presentation.

 
Prof Joseph Zohar (Tel Aviv):
Neuroscience Based Nomenclature (NbN): Can neuroscience change an outdated psychotropic classification?
 
Current psychopharmacological nomenclature remains wedded to earlier period of scientific understanding, fails to reflect contemporary developments and knowledge, does not help clinicians to select the best medication for a given patient, and tends to confuse patients as they are being given a drug with a different name compared to their identified diagnosis (e.g. "Antipsychotic" for depression).
Four major colleges of Neuropsychopharmacology (ECNP, ACNP, Asian CNP, and CINP together with IUPHAR) proposed a new pharmacologically-driven nomenclature focusing on Pharmacological Target and Mode of Action, including 4 layers of additional information: (1)Approved Indications, (2)Efficacy and side effects, (3)Practical note, and (4)Neurobiology. Several surveys in four different continents were conducted in order to examine satisfaction with the current psychopharmalogical nomenclature, as well as test the four-axis template. The results of the surveys suggest that clinicians found the available nomenclature system dissatisfactory and many times confusing for them and the patients. The proposed nomenclature seeks to up-end current usage by placing Pharmacological Target and Mode of Action rather than indication as the primary driven force.
 
In this lecture examples of using the NbN in key medications will be presented and discussed.
 
 
Tuition fees and grants 2015 - 2016
The tuition fees for the next academic year, starting with the Summer Course, are published on the website. Note that the tuition fee can only be paid by bank transfer.
Also, the regulations concerning the Grants have been updated. For next year there are two  Grants of €1000 each: 1 Spinoza and 1 Board grant. Send in your application before 15 April 2015
 
http://affect-neuroscience.org